In this video, San Diego criminal defense attorney Ryan Tegnelia explains how prescription medications, even when used responsibly, can lead to DUI arrest. Prescription medication can be legally prescribed and taken as ordered by a doctor and still lead to a DUI. This is because many medications impair our abilities to operate a motor vehicle safely. If a doctor thinks you won’t be able to drive safely, take their advice. A prescription medication DUI is possible even if the medications do not carry a printed warning on the bottle against operating a vehicle.